Alopecia X Treatment

Alopecia X is a common cause of noninflammatory alopecia in Pomeranian dogs. Some treatments work well for some dogs with Alopecia X but those same treatments dont work at all for dogs with the same symptoms.

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Abstract Sixteen Pomeranians and eight miniature poodles presenting with clinical signs of alopecia X elevated blood concentrations of 17-hydroxyprogesterone post stimulation with adrenocorticotropic hormone and increased urinary cortisolcreatinine ratios were treated with trilostane a competitive inhibitor of 3β-hydroxysteroid dehydrogenase.

Alopecia x treatment. Treatment of canine Alopecia X with trilostane. Your genes and your environment seem to play roles in causing androgenic alopecia. In the past treatment with growth hormone injections resulted in hair regrowth in many individuals.

Previous treatments with deslorelin melatonin and topical minoxidil had failed to produce significant hair regrowth. The dogs were anaesthetized and the skin was punctured with a microneedling device. For this reason the first step in treatment is to sterilize the patient.

In my opinion in hair cycle arrest the potential risk of side effects with the use of mitotane or trilostane outweigh the potential benefit of possible hair regrowth in this otherwise cosmetic condition. Dogs were followed over a period of 12 months. Unspayed females should be spayed intact males should be neutered.

Treatments have variable success in regrowing hair and some are actually risky for the patient. According to the University of Tennessees web page on hair loss supplementation with oral melatonin has benefits in. The dogs are otherwise healthy but they experience partial hair loss to complete baldness.

Medical treatment options which can cause hair regrowth in some animals include. An old treatment that was fairly successful was administering growth hormone. Many different therapies have been advocated for management of Alopecia X including neutering entire animals melatonin methyl testosterone growth hormone trilostane deslorelin acetate or monitoring without specific therapy.

Alopecia X is a cosmetic disorder which often does not warrant aggressive treatment. If youre a man the condition often leads to complete or partial baldness. Corticosteroid injections are often used in the treatment of alopecia areata as they work by modulating immune system activity and lowering inflammation.

There are many causes of hair loss but alopecia X refers to a non-inflammatory mainly symmetrical condition in which there is hair cycle arrest. Topical Corticosteroids This form of treatment acts by decreasing the inflammation around the hair follicle and reducing hair loss. As you may have guessed from the term castration-responsive alopecia the hair may regrow several months after the dog is spayed or neutered.

Two neutered female Pomeranian siblings with histologically confirmed alopecia X. Sixteen Pomeranians and eight miniature poodles presenting with clinical signs of alopecia X elevated blood concentrations of 17-hydroxyprogesterone post stimulation with adrenocorticotropic hormone and increased urinary cortisolcreatinine ratios were treated with trilostane a competitive inhibit. Melatonin trilostane and lysodren.

Neutering of intact dogs is recommended and often causes temporary or permanent hair regrowth due to alteration of hormonal levels. Alopecia X unlike other forms of alopecia is not related to hormonal imbalances in the body. Do you think your dog is suffering from Alopecia X.

Alopecia X seems to be a sex hormone imbalance in at least some cases and didnt earn the name Castration Responsive Alopecia for nothing. Other treatments one might come across include mitotane and trilostane. Hair has a cyclical growth pattern comprising a growth phase anagen a transitional phase catagen and a resting phase telogen.

Vets cant even decide on how to treat the disease. Progesterone can induce mammary-derived growth hormone and is used to treat dogs with congenital growth hormone deficiency. Alopecia X has been described in many plush-coated dog breeds including the Pomeranian and the Chow Chow.

Alopecia is the loss of hair in areas which were previously haired. According to the National Alopecia Areata Foundation highly.

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