How To Treat The Cytokine Storm

For instance avoid eating too much sugar get plenty of sleep and follow a healthy lifestyle. In the context of COVID-19 doctors are currently using immunosuppressants like the steroid dexamethasone selective cytokine inhibitors and anti-inflammatory drugs like the ones used to treat rheumatoid arthritis example.

The Pathogenesis And Treatment Of The Cytokine Storm In Covid 19 Journal Of Infection

It significantly improved the 28-day survival rate of patients with severe sepsis71There is currently no clinical experience with applying specific IL-1 family blockers to treat COVID-19.

How to treat the cytokine storm. Anakinra an antagonist of IL-1β can be used to treat the cytokine storm caused by infection. Short-term use of dexamethasone a synthetic corticosteroid has been demonstrated to reduce the severity of inflammation and lung damage induced by a cytokine storm by inhibiting the severe cytokine storm or the hyperinflammatory phase in patients with COVID-19. Consider the GAPS diet or an autoimmune paleo AIP keto or paleo diet.

For example blood levels of the protein ferritin may rise as may blood concentrations of the inflammation indicator C-reactive protein which is made by the liver. Tocilizumab which is also a known IL-6 inhibitor to reduce the chances of severe illness and death in COVID-19 patients. Once in the hospital with severe CoVid-19 doctors work hard to treat the patients cytokine storm with medications and other medical methods.

Once immunologic complications like cytokine storm occur anti-viral treatment alone is not enough and should be combined with appropriate anti-inflammatory treatment. Clinical trials continue to identify causes of cytokine storms in COVID-19 cases. Several approaches are currently being used to treat the observed cytokine storm associated with COVID-19 and expectations are especially high for new cytokine-targeted therapies such as tocilizumab anakinra and baricitinib.

Recently cytokine storms also have been noted in patients treated with the new chimeric antigen receptor T-cell therapy CAR-T as immunotherapy for cancer. This treatment saved mice from dying during infection with SARS-CoV-2 the virus responsible for COVID-19. Support your immune system to ensure youre getting the right cytokine immune response.

In some situations it may be possible to treat the underlying source of the cytokine storm. Fortunately with lifestyle changes even the worst cytokine storm can be quelled. For example if cytokine storm is caused by a bacterial infection an antibiotic may be helpful.

Another option is corticosteroids. CAR-T saves the patients life but it also triggers this. Kanneganti and her colleagues used similar drugs to stop TNF-alpha and IFN-gamma in mice.

If you have an advanced cytokine storm inflammation or autoimmune disease you may want to go beyond single foods and transform your whole diet. They see that in about 20 to 30 of cases Cron said. Tocilizumab is a monoclonal antibody that suppresses the immune response by blocking receptors for a key cytokine known as interleukin-6 IL-6.

Though theres no fail-safe diagnostic test there are signs that a storm may be underway. There is a nutritional supplement Cell Shield RTQ that contains Resveratrol Turmeric and Quercetin which are all substances that help suppress a cytokine storm if taken while your immune system is battling the flu. Also drugs that stop TNF-alpha and IFN-gamma from functioning are already FDA approved and used to treat inflammatory diseases.

For example tocilizumab Actemra and siltuximab Sylvant reduce the action of the cytokine interleukin-6. However in many cases a direct treatment for the underlying condition is not available and clinicians must try other approaches to try to decrease the immune response. Once again my takeaway from this topic is that it is best practice to build health prior to becoming exposed to viruses so that your body has a better chance at battling any potential illness.

Doctors are only now coming to understand cytokine storms and how to treat them he adds.

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